RAF Typhoon FGR4s have joined forces with French aircraft in a joint strike on an underground arms cache in Syrian territory used by the IS group, according to the UK's MoD.
The location, located using intelligence, was thought to be housing weapons and explosive materials, the release indicated, and was positioned in mountainous terrain just north of the historic site of Palmyra in the heart of Syria.
"The RAF jets used precision-guided Paveway IV munitions to hit a several access tunnels leading to the facility... initial indications indicate the target was engaged successfully," officials stated.
There was no indication of any harm to civilians in the strike conducted Saturday night and each participating jet returned safely, the ministry further stated.
The Typhoon fighters were backed up by a Voyager aerial refuelling aircraft.
Daesh - referred to as ISIS - established extremist governance over large swathes of Iraq and Syria before its territorial defeat in 2019.
"This strike underscores our UK leadership, and resolve to work closely with our allies, to eliminate any re-emergence of the terrorist group and their violent and radical beliefs in the Middle East," UK Defence Secretary the Defence Secretary stated.
RAF aircraft have carried out overwatch operations over Syrian airspace to "prevent any efforts to regroup" of IS after its defeat at the climactic battle in Baghuz in 2019, the authorities noted.
"I must thank every member of British forces involved in this mission for their expertise and their bravery," he commented. "They were part of numerous British personnel deployed over Christmas and New Year. This mission, to take out terrorist threats who pose a risk to our way of life, shows how our armed forces are always on standby, continuously, protecting the UK domestically and strong abroad."
In December, the US military conducted what it described as a "massive strike" targeting IS targets in Syria, following an ambush resulted in the deaths of two US troops and a civilian linguist in Palmyra.
The UN estimates Islamic State still has between 5,000 and 7,000 militants in both countries.
